Research

The Zhuang research lab works on the forefront of single-molecule biology and bioimaging, developing and applying advanced optical imaging techniques to study the behavior of individual biological molecules and complexes in vitro and in live cells. Students in the Zhuang lab apply their diverse backgrounds in biology, chemistry, physics and engineering to develop new imaging methods and applying these methods to a variety of interesting biological systems. Our current research is focused on three major directions: (1) Developing super-resolution optical microscopy that allows cell and tissue imaging with nanoscopic scale resolution and applying this technology to cell biology and neurobiology, (2) investigating how biomolecules function, especially how proteins and nucleic acids interact, using single-molecule fluorescence imaging and spectroscopy; (3) developing live-cell imaging techniques for studying cellular dynamics, in particular virus-cell interactions.

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Xiaowei Zhuang Howard Hughes Medical Institute Investigator Professor of Chemistry and Chemical Biology Professor of Physics Harvard University 12 Oxford Street Cambridge, MA, 02138 Tel: (617) 496-9558 Fax: (617) 496-9559 email: zhuang@chemistry.harvard.edu Administrator: Matthew Kilroy Tel: (617) 384-9818 email: kilroy@chemistry.harvard.edu